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308 Mechanistically, several posttranslational modifications of proteins, including phosphorylation, ubiquitination, acetylation, O-GlcNAcylation, and methylation, are involved in the regulation of key Hippo/YAP signaling processes by integrating factors and other signaling pathways

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The Thr308 phosphorylation site serves as a pivotal regulatory point through which CaMKK2, as well as 3-phosphoinositide-dependent kinase-1 (PDK1), trigger the activation of Akt/PKB [87, 142]

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Lifestyle Modifications : Emphasizing a healthy lifestyle can be instrumental in maintaining weight loss after discontinuing GLP-1 medications